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Article Date: 07/25/2008

SBUMC Awarded High-End Instrumentation Grant from NIH to Advance Biomedical Research of Diseases
Stony Brook University Medical Center received a 2008 High-End Instrumentation Grant from the National Center for Research Resources, part of the National Institutes of Health (NIH), for the purchase of a mass spectrometer with extremely high resolving power. The instrument, which accurately measures the mass of individual molecules, will enable researchers to discover and characterize proteins and novel diagnostic biomarkers in major diseases such as cancer, diabetes, and cardiovascular disease.

Called the Orbitrap XL Hybrid FT Mass Spectrometer System, the instrument cost more than $850,000 and will be shared by 13 SBUMC scientists for numerous biomedical research projects. This July the NIH awarded 20 high-end instrumentation grants worth a total of $33.3 million to only 18 institutions nationwide. Each grant is to support the purchase of sophisticated equipment costing more than $750,000.

The advanced spectrometry system will be used to advance many research projects by SBU biomedical investigators. These include characterizing the platelet proteome regarding blood disorders, the chemical biology of tuberculosis and fertilization, a proteomic analysis of peritoneal fluid specimens from ovarian cancer patients, blood plasma proteomics in pediatric multiple sclerosis, and in vivo protein biomarkers of exposure and effects of radiation.

Website Address: http://commcgi.cc.sunysb.edu/artman/publish/

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